Histone H3K9Me3 (1-24) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K9Me3 (1-24) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-25 of the human histone H3 sequence. Trimethylation of histone H3 at lysine 9 is associated with gene repression, prevents transcription factor binding, and is a target of the heterochromatin protein 1 (HP1) family proteins CBX1, CBX3, and CBX5. It is recognized by the plant homeodomain fingers of chromodomain helicase DNA binding protein 4 (CHD4), a member of the NuRD deacetylase complex that is upregulated in a variety of cancers and implicated in the DNA damage response.Formal Name: L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-6-(trimethylammonio)-L-norleucyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutaminyl-L-leucyl-L-alanyl-L-threonyl-L-lysyl-L-alanine, trifluoroacetate salt. Synonyms: ARTKQTAR-K(Me3)-STGGKAPRKQLATKA, H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me3)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-OH, H3K9me3, [Lys(Me3)9]-Histone H3 (1-24), Histone H3 (1-24) (Lys9me3). Molecular Formula: C110H202N40O32 . XCF3COOH. Formula Weight: 2597.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.C[N+](C)(C)CCCC[C@H](NC([C@@H](NC([C@H](C)NC([C@@]([H])(NC([C@@H](NC([C@@H](NC([C@@]([H])(NC([C@@H](NC([C@H](C)N[H])=O)CCCNC(N)=N)=O)[C@H](O)C)=O)CCCCN)=O)CCC(N)=O)=O)[C@H](O)C)=O)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@]([H])(C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@]([H])(C(N[C@H](C(N[C@@H](C)C([O-])=O)=O)CCCCN)=O)[C@H](O)C)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)=O)=O)[C@H](O)C)=O)CO)=O. InChi Code: InChI=1S/C110H202N40O32.C2HF3O2/c1-55(2)51-75(99(173)129-58(5)88(162)145-84(63(10)154)104(178)141-66(30-16-21-43-112)90(164)132-60(7)107(181)182)143-96(170)73(38-40-78(116)156)138-91(165)67(31-17-22-44-113)136-94(168)71(35-26-47-125-109(120)121)140-101(175)77-37-28-49-149(77)106(180)59(6)131-89(163)65(29-15-20-42-111)133-81(159)53-127-80(158)52-128-102(176)82(61(8)152)146-100(174)76(54-151)144-95(169)68(33-19-24-50-150(12,13)14)137-93(167)70(34-25-46-124-108(118)119)135-87(161)57(4)130-103(177)83(62(9)153)147-98(172)74(39-41-79(117)157)139-92(166)69(32-18-23-45-114)142-105(179)85(64(11)155)148-97(171)72(134-86(160)56(3)115)36-27-48-126-110(122)123,3-2(4,5)1(6)7/h55-77,82-85,151-155H,15-54,111-115H2,1-14H3,(H38-,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,156,157,158,159,160,161,162,163,164,165,166,167,168,169,170,171,172,173,174,175,176,177,178,179,181,182),(H,6,7)/t56-,57-,58-,59-,60-,61+,62+,63+,64+,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,82-,83-,84-,85-,/m0./s1. InChi Key: YOSRXBYHBVHOKO-VBDFDSPJSA-N.