Histone H3K9Me1 (3-17) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K9Me1 (3-17) is a peptide fragment of histone H3 that corresponds to amino acid residues 4-18 of the human histone H3 sequence. Monomethylation of histone H3 at lysine 9 is found at euchromatin regions of silenced genes and is correlated with gene repression. Recognition of H3K9Me1 by the H3K9 demethylases GLP and G9a is essential to embryonic stem cell differentiation and viability in mice. Cytoplasmic expression of H3K9Me1 is associated with reduced disease-specific mortality risk in patients with oral and/or oropharyngeal squamous cell carcinoma.Formal Name: N2-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-N6-methyl-L-lysyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginine, trifluoroacetate salt. Synonyms: Histone H3 (3-17) (Lys9me1), [Lys(Me1)9]-Histone H3 (3-17), TKQTAR-K(Me1)-STGGKAPR. Molecular Formula: C66H121N25O21 . XCF3COOH. Formula Weight: 1600.8. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.CNCCCC[C@@H](C(N[C@@H](CO)C(N[C@]([C@@H](C)O)([H])C(NCC(NCC(N[C@@H](CCCCN)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@@]([C@@H](C)O)([H])N[H])=O)=O)=O)=O)C)=O)=O. InChi Code: InChI=1S/C66H121N25O21.C2HF3O2/c1-33(80-62(109)51(37(5)95)90-57(104)42(22-23-46(69)96)85-54(101)40(17-8-11-25-68)86-60(107)49(70)35(3)93)52(99)83-41(19-13-27-76-65(71)72)55(102)84-39(18-9-12-26-75-6)56(103)88-44(32-92)58(105)89-50(36(4)94)61(108)79-30-47(97)78-31-48(98)82-38(16-7-10-24-67)53(100)81-34(2)63(110)91-29-15-21-45(91)59(106)87-43(64(111)112)20-14-28-77-66(73)74,3-2(4,5)1(6)7/h33-45,49-51,75,92-95H,7-32,67-68,70H2,1-6H3,(H2,69,96)(H,78,97)(H,79,108)(H,80,109)(H,81,100)(H,82,98)(H,83,99)(H,84,102)(H,85,101)(H,86,107)(H,87,106)(H,88,103)(H,89,105)(H,90,104)(H,111,112)(H4,71,72,76)(H4,73,74,77),(H,6,7)/t33-,34-,35+,36+,37+,38-,39-,40-,41-,42-,43-,44-,45-,49-,50-,51-,/m0./s1. InChi Key: BWSPVERZIVXQLP-UPWAJGABSA-N.