Histone H3K9Ac (1-24) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K9Ac (1-24) is a peptide fragment that corresponds to amino acid residues 2-25 of the human histone H3 sequence. Acetylation of histone H3 at lysine 9 is associated with active gene transcription and can recruit the super elongation complex to chromatin through direct binding with the AF9 and ENL subunits. It increases at the IFN-beta promoter in HeLa cells upon infection with Sendai virus. Acetylation of histone H3 at lysine 9 decreases following induction of DNA damage in HeLa and U2OS cells.Synonyms: ARTKQTAR-K(Ac)-STGGKAPRKQLATKA, H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Ac)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-OH, Histone H3 (1-24) (Lys9ac), [Lys(Ac)9]-Histone H3 (1-24). Molecular Formula: C109H198N40O33 . XCF3COOH. Formula Weight: 2597.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: O=C(O)C(F)(F)F.OC[C@@H](C(N[C@]([H])(C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@]([H])(C(N[C@H](C(N[C@@H](C)C(O)=O)=O)CCCCN)=O)[C@H](O)C)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)=O)=O)[C@H](O)C)=O)NC([C@@H](NC([C@@H](NC([C@H](C)NC([C@@]([H])(NC([C@@H](NC([C@@H](NC([C@@]([H])(NC([C@@H](NC([C@H](C)N[H])=O)CCCNC(N)=N)=O)[C@H](O)C)=O)CCCCN)=O)CCC(N)=O)=O)[C@H](O)C)=O)=O)CCCNC(N)=N)=O)CCCCNC(C)=O)=O. InChi Code: InChI=1S/C109H198N40O33.C2HF3O2/c1-53(2)49-74(98(173)129-56(5)87(162)145-83(61(10)153)103(178)141-65(28-14-19-41-111)89(164)132-58(7)106(181)182)143-95(170)72(36-38-77(115)156)138-90(165)66(29-15-20-42-112)136-93(168)70(33-24-46-125-108(119)120)140-100(175)76-35-26-48-149(76)105(180)57(6)131-88(163)64(27-13-18-40-110)133-80(159)51-127-79(158)50-128-101(176)81(59(8)151)146-99(174)75(52-150)144-94(169)67(31-17-22-44-123-63(12)155)137-92(167)69(32-23-45-124-107(117)118)135-86(161)55(4)130-102(177)82(60(9)152)147-97(172)73(37-39-78(116)157)139-91(166)68(30-16-21-43-113)142-104(179)84(62(11)154)148-96(171)71(134-85(160)54(3)114)34-25-47-126-109(121)122,3-2(4,5)1(6)7/h53-62,64-76,81-84,150-154H,13-52,110-114H2,1-12H3,(H2,115,156)(H2,116,157)(H,123,155)(H,127,158)(H,128,176)(H,129,173)(H,130,177)(H,131,163)(H,132,164)(H,133,159)(H,134,160)(H,135,161)(H,136,168)(H,137,167)(H,138,165)(H,139,166)(H,140,175)(H,141,178)(H,142,179)(H,143,170)(H,144,169)(H,145,162)(H,146,174)(H,147,172)(H,148,171)(H,181,182)(H4,117,118,124)(H4,119,120,125)(H4,121,122,126),(H,6,7)/t54-,55-,56-,57-,58-,59+,60+,61+,62+,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,81-,82-,83-,84-,/m0./s1. InChi Key: NHUBDECCQQGUGJ-JHDGBBSQSA-N.