Histone H3K9Ac (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K9Ac (1-21) is an N-terminal peptide fragment that corresponds to amino acid residues 2-22 of the human histone H3 sequence. Acetylation of histone H3 at lysine 9 is associated with active gene transcription and can recruit the super elongation complex to chromatin through direct binding with the AF9 and ENL subunits. It increases at the IFN-beta promoter in HeLa cells upon infection with Sendai virus. Acetylation of histone H3 at lysine 9 decreases following induction of DNA damage in HeLa and U2OS cells.Formal Name: L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-N6-acetyl-L-lysyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutaminyl-L-leucyl-L-alanine, trifluoroacetate salt. Synonyms: ARTKQTAR-K(Ac)-STGGKAPRKQLA, Histone H3 (1-21) (Lys9ac), [Lys(Ac)9]-Histone H3 (1-21). Molecular Formula: C96H174N36O29 . XCF3COOH. Formula Weight: 2296.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: NCCCC[C@H](NC([C@@]([H])(NC([C@@H](NC([C@H](C)N)=O)CCCNC(N)=N)=O)[C@H](O)C)=O)C(N[C@H](C(N[C@]([H])(C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)=O)=O)[C@H](O)C)=O)CO)=O)CCCCNC(C)=O)=O)CCCNC(N)=N)=O)=O)[C@H](O)C)=O)CCC(N)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C96H174N36O29.C2HF3O2/c1-47(2)43-65(86(153)117-51(6)93(160)161)127-83(150)63(31-33-68(101)138)123-78(145)57(24-12-16-36-98)121-81(148)61(28-20-40-111-95(105)106)125-88(155)67-30-22-42-132(67)92(159)50(5)116-77(144)56(23-11-15-35-97)118-71(141)45-113-70(140)44-114-89(156)72(52(7)134)129-87(154)66(46-133)128-82(149)58(26-14-18-38-109-55(10)137)122-80(147)60(27-19-39-110-94(103)104)120-76(143)49(4)115-90(157)73(53(8)135)130-85(152)64(32-34-69(102)139)124-79(146)59(25-13-17-37-99)126-91(158)74(54(9)136)131-84(151)62(119-75(142)48(3)100)29-21-41-112-96(107)108,3-2(4,5)1(6)7/h47-54,56-67,72-74,133-136H,11-46,97-100H2,1-10H3,(H2,101,138)(H2,102,139)(H,109,137)(H,113,140)(H,114,156)(H,115,157)(H,116,144)(H,117,153)(H,118,141)(H,119,142)(H,120,143)(H,121,148)(H,122,147)(H,123,145)(H,124,146)(H,125,155)(H,126,158)(H,127,150)(H,128,149)(H,129,154)(H,130,152)(H,131,151)(H,160,161)(H4,103,104,110)(H4,105,106,111)(H4,107,108,112),(H,6,7)/t48-,49-,50-,51-,52+,53+,54+,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,72-,73-,74-,/m0./s1. InChi Key: UZMYPEUNVJIGCC-GPCQWBSUSA-N.