Histone H3K4Me1 (1-21) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K4Me1 (1-21) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 2-22 of the human histone H3 sequence. Monomethylation of histone H3 at lysine 4 is found at active and primed enhancer regions of gene promoters and H3K4Me1-containing nucleosomes are more efficiently remodeled by the chromatin-remodeling complex BAF than unmarked nucleosomes. It is also enriched at CpG sites associated with aging in stem and differentiated cells.Formal Name: L-alanyl-L-arginyl-L-threonyl-N6-methyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutaminyl-L-leucyl-L-alanine, trifluoroacetate salt. Synonyms: ART-K(Me1)-QTARKSTGGKAPRKQLA, Histone H3 (1-21) (Lys4me1), [Lys(Me1)4]-Histone H3 (1-21). Molecular Formula: C95H174N36O28 . XCF3COOH. Formula Weight: 2268.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: CNCCCC[C@H](NC([C@@]([H])(NC([C@@H](NC([C@H](C)N)=O)CCCNC(N)=N)=O)[C@H](O)C)=O)C(N[C@H](C(N[C@]([H])(C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([H])(C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C)C(O)=O)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)=O)=O)[C@H](O)C)=O)CO)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)[C@H](O)C)=O)CCC(N)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C95H174N36O28.C2HF3O2/c1-47(2)43-64(85(151)116-51(6)92(158)159)126-82(148)62(31-33-67(100)136)122-77(143)56(24-12-16-36-97)120-80(146)60(28-20-40-110-94(104)105)124-87(153)66-30-22-42-131(66)91(157)50(5)115-76(142)55(23-11-15-35-96)117-70(139)45-112-69(138)44-113-88(154)71(52(7)133)128-86(152)65(46-132)127-81(147)57(25-13-17-37-98)121-79(145)59(27-19-39-109-93(102)103)119-75(141)49(4)114-89(155)72(53(8)134)129-84(150)63(32-34-68(101)137)123-78(144)58(26-14-18-38-108-10)125-90(156)73(54(9)135)130-83(149)61(118-74(140)48(3)99)29-21-41-111-95(106)107,3-2(4,5)1(6)7/h47-66,71-73,108,132-135H,11-46,96-99H2,1-10H3,(H2,100,136)(H2,101,137)(H,112,138)(H,113,154)(H,114,155)(H,115,142)(H,116,151)(H,117,139)(H,118,140)(H,119,141)(H,120,146)(H,121,145)(H,122,143)(H,123,144)(H,124,153)(H,125,156)(H,126,148)(H,127,147)(H,128,152)(H,129,150)(H,130,149)(H,158,159)(H4,102,103,109)(H4,104,105,110)(H4,106,107,111),(H,6,7)/t48-,49-,50-,51-,52+,53+,54+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,71-,72-,73-,/m0./s1. InChi Key: GEWNTJCMVHBRNK-UFXXRFMKSA-N.