Glutaurine

Glutaurine is a dipeptide composed of L-glutamic acid (Cay-30377) and taurine (Cay-27031) that has been found in rat brain. It is formed from glutathione and taurine by gamma-glutamyl transpeptidase. Glutaurine enhances potassium-induced release of L-glutamate and inhibits kainate-induced formation of cGMP in isolated mouse cerebral cortical slices when used at concentrations of 0.1 and 1 mM, respectively. It decreases plasma levels of triiodothyronine (T3) and increases plasma thyroid-stimulating hormone (TSH) levels in rats when administered at a dose of 600 µg/kg. Glutaurine (50 µg/animal, p.o.) prevents electroconvulsive shock-induced amnesia in rats.Formal Name: N-(2-sulfoethyl)-L-glutamine. CAS Number: 56488-60-9. Synonyms: gamma-Glutamyl Taurine, gamma-L-Glutamyl Taurine. Molecular Formula: C7H14N2O6S. Formula Weight: 254.3. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: OC([C@@H](N)CCC(NCCS(=O)(O)=O)=O)=O. InChi Code: InChI=1S/C7H14N2O6S/c8-5(7(11)12)1-2-6(10)9-3-4-16(13,14)15/h5H,1-4,8H2,(H,9,10)(H,11,12)(H,13,14,15)/t5-/m0/s1. InChi Key: WGXUDTHMEITUBO-YFKPBYRVSA-N.