Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide (Cay-40231, Cay-29969, Cay-40170).Formal Name: 3S-carboxy-30S-[(1,1-dimethylethoxy)carbonyl]-9,18,27,32-tetraoxo-11,14,20,23-tetraoxa-2,8,17,26,31-pentaazanonatetracontanedioic acid, 49-(1,1-dimethylethyl) 1-(9H-fluoren-9-ylmethyl) ester. CAS Number: 1662688-20-1. Synonyms: Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH. Molecular Formula: C64H101N5O16. Formula Weight: 1196.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO: soluble: >10 mg/ml, Ethanol: Soluble: >10 mg/ml, PBS (pH 7.2): Slightly Soluble: 0.1-1 mg/ml. SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O)=O)C(OC(C)(C)C)=O)=O)=O)=O)C(O)=O. InChi Code: InChI=1S/C64H101N5O16/c1-63(2,3)84-59(74)33-20-18-16-14-12-10-8-7-9-11-13-15-17-19-32-56(71)68-54(61(77)85-64(4,5)6)34-35-55(70)66-37-39-79-41-44-82-47-58(73)67-38-40-80-42-43-81-46-57(72)65-36-26-25-31-53(60(75)76)69-62(78)83-45-52-50-29-23-21-27-48(50)49-28-22-24-30-51(49)52/h21-24,27-30,52-54H,7-20,25-26,31-47H2,1-6H3,(H,65,72)(H,66,70)(H,67,73)(H,68,71)(H,69,78)(H,75,76)/t53-,54-/m0/s1. InChi Key: COTQASXXEXJBOM-PJYGOTMFSA-N.