Cyclosporin D
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-TP1665-1mg | 1 mg | - |
7 - 10 business days* |
259.00€
|
|||
| TGM-TP1665-5mg | 5 mg | - |
7 - 10 business days* |
586.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds... more
Product information "Cyclosporin D"
Description: Cyclosporin D is a metabolite of cyclosporin A, an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells. Smiles: C\C=C\C[C@@H](C)[C@@H](O)[C@@H]1N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](NC1=O)C(C)C)C(C)C. References: Gschwendt M, et al. The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro. Biochem Biophys Res Commun. 1988 Jan 29,150(2):545-51.
| Supplier: | TargetMol |
| Supplier-Nr: | TP1665 |
Properties
| Application: | Potent TPA/PMA effects inhibitor, Antifungal, immunosuppressant, calcineurin inhibitor |
| Conjugate: | No |
| MW: | 1216.662 D |
| Formula: | C63H113N11O12 |
Database Information
| CAS : | 63775-96-2| Matching products |
| KEGG ID : | K17611 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302, H350, H362 |
| P Phrases: | P201, P202, P260, P263, P264, P270, P280, P330, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed