cyclo(RGDyC) (trifluoroacetate salt)

cyclo(RGDyC) is a cyclic pentapeptide that contains the alphaVbeta3 integrin-binding sequence arginine-glycine-aspartate (RGD). It has been used to generate doxorubicin-containing liposomes and fluorescent silicon nanoparticles to target tumors and ocular neovasculature, respectively.Formal Name: 2-((2S,5R,8R,11S)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-8-(mercaptomethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid, trifluoroacetate salt. Synonyms: c(RGDyC), cyclo(Arg-Gly-Asp-D-Tyr-Cys). Molecular Formula: C24H34N8O8S . XCF3COOH. Formula Weight: 594.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Water: soluble. SMILES: O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CS)[C@H]1CC2=CC=C(C=C2)O.FC(F)(F)C(O)=O. InChi Code: InChI=1S/C24H34N8O8S.C2HF3O2/c25-24(26)27-7-1-2-14-20(37)28-10-18(34)29-16(9-19(35)36)22(39)31-15(8-12-3-5-13(33)6-4-12)21(38)32-17(11-41)23(40)30-14,3-2(4,5)1(6)7/h3-6,14-17,33,41H,1-2,7-11H2,(H,28,37)(H,29,34)(H,30,40)(H,31,39)(H,32,38)(H,35,36)(H4,25,26,27),(H,6,7)/t14-,15+,16-,17-,/m0./s1. InChi Key: AZBISXDKFNGVPV-ZSXFUQLHSA-N.