Angiotensin I (human, rat, mouse) (trifluoroacetate salt)

Angiotensin I is an endogenous peptide that is converted to the vasoconstrictor angiotensin II (Cay-17150) by angiotensin-converting enzyme (ACE). It binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM) and increases renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM). In vivo, angiotensin I (5 µg/kg, i.c.v.) increases mean arterial pressure (MAP) and plasma arginine vasopressin (AVP) level in fetal ewes.Formal Name: 5-L-isoleucine-angiotensin I, trifluroracetate salt. Molecular Formula: C62H89N17O14 . XCF3COOH. Formula Weight: 1296.5. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: C[C@@H](CC)[C@]([H])(NC([C@@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)CC1=CC=C(C=C1)O)=O)C(N[C@@H](CC2=CNC=N2)C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CC4=CN=CN4)=O)CC5=CC=CC=C5)=O)CCC3)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C62H89N17O14.C2HF3O2/c1-7-35(6)51(78-56(87)44(25-37-17-19-40(80)20-18-37)74-58(89)50(34(4)5)77-53(84)42(15-11-21-68-62(64)65)71-52(83)41(63)28-49(81)82)59(90)75-46(27-39-30-67-32-70-39)60(91)79-22-12-16-48(79)57(88)73-43(24-36-13-9-8-10-14-36)54(85)72-45(26-38-29-66-31-69-38)55(86)76-47(61(92)93)23-33(2)3,3-2(4,5)1(6)7/h8-10,13-14,17-20,29-35,41-48,50-51,80H,7,11-12,15-16,21-28,63H2,1-6H3,(H,66,69)(H,67,70)(H,71,83)(H,72,85)(H,73,88)(H,74,89)(H,75,90)(H,76,86)(H,77,84)(H,78,87)(H,81,82)(H,92,93)(H4,64,65,68),(H,6,7)/t35-,41-,42-,43-,44-,45-,46-,47-,48-,50-,51-,/m0./s1. InChi Key: XMNUWKLIJQRDTJ-AHYCRNLZSA-N.