Ac-DEVD-AFC

Description: Ac-DEVD-AFC, a fluorogenic substrate, undergoes cleavage by caspase-3, producing a blue fluorescent compound upon excitation at 400 nm, which can be quantified at an emission maximum of 505 nm. Target: Others. Smiles: CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F. References: Tao Z , Goodisman J , Penefsky H S , et al. Caspase activation by anticancer drugs: the caspase storm.[J]. Molecular Pharmaceutics, 2007, 4(4):583.