Tumor Necrosis Factor Ligand Superfamily Member 9, active (TNFSF9), Recombinant, Human

Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269, PubMed:20032458}. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL­8 production using human PBMC is less than 10ng/ml, corresponding to a specific activity of ? 1.0x10e5 IU/mg. Sequence: REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE, Molecular Weight: 19.4kD, PubMed ID: 8088337, 15489334, 20032458, Gene Name: TNFSF9, Swiss Prot: P41273, Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.