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![TNF-alpha protein (His tag), recombinant rabbit](https://www.biomol.com/media/image/35/18/99/E-PDEO100005-20_600x600.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PDEO100005.20 | 20 µg | - |
7 - 16 business days* |
81.00€
|
|||
E-PDEO100005.100 | 100 µg | - |
7 - 16 business days* |
141.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Activity: Testing in progress Protein Construction: A DNA sequence encoding the Rabbit TNF-alpha... more
Product information "TNF-alpha protein (His tag), recombinant rabbit"
Activity: Testing in progress Protein Construction: A DNA sequence encoding the Rabbit TNF-alpha protein (P04924) (Leu 80-Leu 235) was expressed with a N-His tag. Sequence: Leu 80-Leu 235. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 18 kDa. Protein function: Tumor necrosis factor alpha (TNFalpha) is the prototypic ligand of the TNF superfamily. TNFalpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFalpha is a pleiotropic c Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6. [The UniProt Consortium]
Keywords: | TNF, TNFA, Recombinant Rabbit TNF-alpha protein (His tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PDEO100005 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | rabbit |
MW: | 17.05 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K03156 | Matching products |
UniProt ID : | P04924 | Matching products |
Gene ID | GeneID 100009088 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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