Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
![sCD40L Protein (Fc Tag) (recombinant human)](https://www.biomol.com/media/image/40/67/15/E-PDMH100209-20_600x600.jpg)
NEW
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PDMH100209.20 | 20 µg | - | - |
7 - 16 business days* |
248.00€
|
||
E-PDMH100209.100 | 100 µg | - | - |
7 - 16 business days* |
742.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Sequence: Met113-Leu261. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg of the protein as determined... more
Product information "sCD40L Protein (Fc Tag) (recombinant human)"
Sequence: Met113-Leu261. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 40-45 kDa. Protein function: The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with an hyper-IgM syndrome. Protein function: Cytokine that acts as a ligand to CD40/TNFRSF5 (PubMed:1280226, PubMed:31331973). Costimulates T-cell proliferation and cytokine production (PubMed:8617933). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B (PubMed:15067037, PubMed:31331973). Induces the activation of kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. [The UniProt Consortium]
Keywords: | CD40L, CD40LG, Recombinant Human sCD40L Protein(Fc Tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PDMH100209 |
Properties
Conjugate: | No |
Host: | Mammalian |
Species reactivity: | human |
Format: | Lyophilized |
Database Information
KEGG ID : | K03161 | Matching products |
UniProt ID : | P29965 | Matching products |
Gene ID | GeneID 959 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed