Progranulin (rat) (rec.)

Progranulin (rat) (rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-40A-0194-C010 10 µg -

3 - 9 business days*

198.00€
AG-40A-0194-C050 50 µg -

3 - 9 business days*

407.00€
 
Signal peptide and rat progranulin (aa 1-602) are fused at the C-terminus to a FLAGR)-tag.... more
Product information "Progranulin (rat) (rec.)"
Signal peptide and rat progranulin (aa 1-602) are fused at the C-terminus to a FLAGR)-tag. Lyophilized from 0.2µm-filtered solution in PBS. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Keywords: Proepithelin, PEPI, PC Cell-derived Growth Factor
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40A-0194

Properties

Application: Metabolic studies
Conjugate: No
Host: Human cells
Species reactivity: rat
MW: 65 kD
Format: Lyophilized

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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