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Macrophage Inflammatory Protein-1 alpha (CCL3), rat recombinant (rrMIP-1a)
Product information "Macrophage Inflammatory Protein-1 alpha (CCL3), rat recombinant (rrMIP-1a)"
Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 69 amino acids. CCL3 activates human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation.
Keywords:
Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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