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LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Description: Transforming growth factor beta (TGFbeta) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFbeta gene product. Extracellular activation of these complexes is a critical step in regulation of TGFbeta function in vivo. The TGFbeta1 LAP is a ligand for the integrin alphavbeta6 and that alphavbeta6-expressing cells induce spatially restricted activition of TGFbeta1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis.
Keywords:
transforming growth factor beta 1, TGFB1, LAP (TGF-beta 1), LAP, TGFB, TGFbeta, TGFbeta, transforming growth factor beta1, CED, LAP (TGF-beta 1), LAP (TGFbeta 1), LAP (TGFbeta 1), DPD1
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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