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![IL-12 (human) (rec.) (His)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-HF-20112-C010 | 10 µg | - | - |
3 - 9 business days* |
248.00€
|
||
CHI-HF-20112-C050 | 50 µg | - | - |
3 - 9 business days* |
715.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic... more
Product information "IL-12 (human) (rec.) (His)"
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells, the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen, and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumor and anti viral agent.
Keywords: | IL12A, NKSF1, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, Interleukin-12, IL-12p70, IL-12p75, Cytotoxic Lymphocyte Maturation Factor, CLMF, N |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | HF-20112 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
MW: | ~85 kD |
Purity: | >95% |
Format: | Lyophilized |
Database Information
KEGG ID : | K05406 | Matching products |
UniProt ID : | P29459 | Matching products |
Gene ID | GeneID 3592 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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