Human TNFSF18 / GITRL recombinant protein (Active)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG70085.20	20 µg		-	-	6 - 14 business days*		336.00€
ARG70085.100	100 µg		-	-	6 - 14 business days*		840.00€

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Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can... more

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Product information "Human TNFSF18 / GITRL recombinant protein (Active)"

Protein function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T- cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation. [The UniProt Consortium]

Keywords:	AITRL, hGITRL, TNFSF18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, Tumor necrosis factor ligand superfamily member 18
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG70085