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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| DIM-PME30024.50 | 50 µg | - | - |
7 - 16 business days* |
704.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant Human Osteoprotegerin is produced by our Mammalian expression system and the target... more
Product information "Human OPG (C-Fc) Protein"
Recombinant Human Osteoprotegerin is produced by our Mammalian expression system and the target gene encoding Glu22-Leu201 is expressed with a Fc tag at the C-terminus.. , Protein function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. [The UniProt Consortium]
| Keywords: | Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF11B, OCIF, OPG |
| Supplier: | DIMA |
| Supplier-Nr: | PME30024 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
| MW: | 47.2 kD |
| Purity: | >95% (SDS-PAGE) |
| Format: | Lyophilized |
Database Information
| CAS : | 12| Matching products |
| KEGG ID : | K05148 | Matching products |
| UniProt ID : | O00300 | Matching products |
| Gene ID | GeneID 4982 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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