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![APRIL (mouse) (multimeric) (rec.)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-40B-0089-C010 | 10 µg | - |
3 - 9 business days* |
352.00€
|
|||
AG-40B-0089-3010 | 30 µg (3 x 10 µg) | - |
3 - 9 business days* |
704.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The extracellular domain of mouse APRIL (amino acids 88-232) is fused at the N-terminus to mouse... more
Product information "APRIL (mouse) (multimeric) (rec.)"
The extracellular domain of mouse APRIL (amino acids 88-232) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-110) and a FLAG(R)-tag. APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. MultimericAPRIL is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the N-terminus of APRIL is required for binding to negatively charged sulfated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumor cells as well as primary lymphoid cells.
Keywords: | MegaAPRIL(TM), soluble (mouse) (rec.), ACRP30headless:APRIL, ACRP30headless:CD256, ACRP30headless:TNFSF13, ACRP30headless:A-proliferation-inducing Ligand |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-40B-0089 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human, mouse |
Format: | Lyophilized |
Database Information
KEGG ID : | K05475 | Matching products |
UniProt ID : | Q9D777 | Matching products |
Gene ID | GeneID 69583 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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