VAC14 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 2349 Sequence: ATGAACCCCG AGAAGGATTT CGCGCCGCTC ACGCCTAACA TCGTGCGCGC CCTCAATGAC AAGCTGTACG AAAAGCGGAA GGTGGCAGCG CTGGAGATCG AGAAGCTGGT CCGGGAGTTC GTGGCCCAGA ACAATACCGT GCAAATCAAG CATGTGATCC AGACCCTGTC CCAGGAGTTT GCCCTGTCTC AGCACCCCCA CAGCCGGAAA GGGGGCCTCA TCGGCCTGGC CGCCTGCTCC ATCGCACTGG GCAAGGACTC AGGGCTCTAC CTGAAGGAGC TGATCGAGCC AGTGCTGACC TGCTTCAATG ATGCAGACAG CAGGCTGCGC TACTATGCCT GCGAGGCCCT CTACAACATC GTCAAGGTGG CCCGGGGCGC TGTGCTGCCC CACTTCAACG TGCTCTTTGA CGGGCTGAGC AAGCTGGCAG CCGACCCAGA CCCCAATGTG AAAAGCGGAT CTGAGCTCCT AGACCGCCTT TTAAAGGACA TTGTGACTGA GAGCAACAAG TTTGACCTGG TGAGCTTCAT CCCCTTGTTG CGAGAGAGGA TTTACTCCAA CAACCAGTAT GCCCGGCAGT TCATCATCTC CTGGATCCTG GTTCTGGAGT CGGTGCCAGA CATTAACCTG CTGGATTACC TGCCGGAGAT CCTGGATGGA CTCTTCCAGA TCCTGGGTGA CAATGGCAAA GAGATTCGCA AAATGTGTGA GGTTGTTCTT GGAGAATTCT TAAAAGAAAT TAAGAAGAAC CCCTCCAGTG TGAAGTTTGC TGAGATGGCC AACATCCTGG TGATCCACTG CCAGACAACA GATGACCTCA TCCAGCTGAC AGCCATGTGC TGGATGCGGG AGTTCATCCA GCTGGCGGGC CGCGTCATGC TGCCTTACTC CTCCGGGATC CTGACTGCTG TCTTGCCCTG CTTGGCCTAC GATGACCGCA AGAAAAGCAT CAAAGAAGTG GCCAACGTGT GCAACCAGAG CCTGATGAAG CTGGTCACCC CCGAGGACGA CGAGCTGGAT GAGCTGAGAC CTGGGCAGAG GCAGGCAGAG CCCACCCCTG ACGATGCCCT GCCAAAGCAG GAGGGCACAG CCAGTGGAGG TCCAGATGGT TCCTGTGACT CCAGCTTCAG TAGCGGCATC AGTGTCTTCA CTGCAGCCAG CACTGAAAGA GCCCCAGTGA CCCTTCACCT CGACGGGATC GTGCAGGTCC TAAACTGCCA CCTCAGTGAC ACGGCCATTG GGATGATGAC CAGGATTGCA GTTCTCAAGT GGCTCTACCA CCTCTACATC AAAACTCCTC GGAAGATGTT CCGGCACACG GACAGCCTCT TTCCCATCCT ACTGCAGACG TTATCGGATG AATCGGATGA GGTGATCCTG AAGGACCTGG AGGTGCTGGC AGAAATCGCT TCCTCCCCCG CAGGCCAGAC GGATGACCCA GGCCCCCTCG ATGGCCCTGA CCTCCAGGCC AGCCACTCAG AGCTCCAGGT GCCCACCCCT GGCAGAGCCG GCCTACTGAA CACCTCTGGT ACCAAAGGCT TAGAATGTTC TCCTTCAACT CCCACCATGA ATTCTTACTT TTATAAGTTC ATGATCAACC TTCTCAAGAG ATTCAGCAGC GAACGGAAGC TCCTGGAGGT CAGAGGCCCT TTCATCATCA GGCAGCTGTG CCTCCTGCTG AATGCGGAGA ACATCTTCCA CTCAATGGCA GACATCCTGC TGCGGGAGGA GGACCTCAAG TTCGCCTCGA CCATGGTCCA CGCCCTCAAC ACCATCCTGC TGACCTCCAC AGAGCTCTTC CAGCTAAGGA ACCAGCTGAA GGACCTGAAG ACCCTGGAGA GCCAGAACCT GTTCTGCTGC CTGTACCGCT CCTGGTGCCA CAACCCAGTC ACCACGGTGT CCCTCTGCTT CCTCACCCAG AACTACCGGC ACGCCTATGA CCTCATCCAG AAGTTTGGGG ACCTGGAGGT CACCGTGGAC TTCCTCGCAG AGGTGGACAA GCTGGTGCAG CTGATTGAGT GCCCCATCTT CACATATCTG CGCCTGCAGC TGCTGGACGT GAAGAACAAC CCCTACCTGA TCAAGGCCCT CTACGGCCTG CTCATGCTCC TGCCGCAGAG CAGCGCCTTC CAGCTGCTCT CGCACCGGCT CCAGTGCGTG CCCAACCCTG AGCTGCTGCA GACCGAAGAC AGTCTAAAGG CAGCCCCCAA GTCCCAGAAA GCTGACTCCC CTAGCATCGA CTACGCAGAG CTGCTGCAGC ACTTTGAGAA GGTCCAGAAC AAGCACCTGG AAGTGCGGCA CCAGCGGAGC GGGCGTGGGG ACCACCTGGA CCGGAGGGTT Protein function: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes. [The UniProt Consortium]