TNFAIP1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 951 Sequence: atgtcggggg acacctgcct gtgcccagcc tcaggggcca agcccaagct cagtggcttc aagggaggag ggttgggcaa caagtatgtc cagctcaacg tgggcggctc tctgtactac accactgtgc gggccctgac ccgccacgac accatgctca aggccatgtt cagtgggcgc atggaggtgc tgaccgacaa agaaggctgg atcctcatag accgttgtgg aaagcacttt ggcaccattt tgaattacct ccgagatgac accatcaccc tccctcagaa ccggcaagaa atcaaggaat tgatggctga agcaaagtat tacctcatcc aggggctggt gaatatgtgc cagagtgccc tgcaggacaa gaaggactcc taccagcctg tgtgcaacat ccccatcatc acatccctaa aggaggagga gcggctcatc gaatcctcca ccaagcccgt ggtgaagctg ctgtacaaca gaagcaacaa caagtattcc tacaccagca actctgacga ccacctgctg aaaaacatcg agctgtttga caagctctcc ctgcgcttca acggccgcgt gctcttcatc aaggatgtca ttggtgacga gatctgctgc tggtcctttt atggccaggg ccgtaagctg gcagaggtgt gctgtacctc catcgtgtat gccacggaga agaagcagac caaggtggaa ttcccagagg cccgaatcta tgaggagaca ctcaacgtcc tactctatga gactccccgc gtccccgaca actccttgtt ggaggccaca agccgtagcc gcagccaggc ttcccccagt gaagatgagg agacctttga actgcgggac cgtgtccgcc gcatccacgt caagcgctac agcacttacg atgaccggca gctcggccac cagtctaccc atcgcgactg Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity. [The UniProt Consortium]