SLC22A6 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1653 Sequence: atggccttta atgacctcct gcagcaggtg gggggtgtcg gccgcttcca gcagatccag gtcaccctgg tggtcctccc cctgctcctg atggcttctc acaacaccct gcagaacttc actgctgcca tccctaccca ccactgccgc ccgcctgccg atgccaacct cagcaagaac ggggggctgg aggtctggct gccccgggac aggcaggggc agcctgagtc ctgcctccgc ttcacctccc cgcagtgggg actgcccttt ctcaatggca cagaagccaa tggcacaggg gccacagagc cctgcaccga tggctggatc tatgacaaca gcaccttccc atctaccatc gtgactgagt gggaccttgt gtgctctcac agggccctac gccagctggc ccagtccttg tacatggtgg gggtgctgct cggagccatg gtgttcggct accttgcaga caggctaggc cgccggaagg tactcatctt gaactacctg cagacagctg tgtcagggac ctgcgcagcc ttcgcaccca acttccccat ctactgcgcc ttccggctcc tctcgggcat ggctctggct ggcatctccc tcaactgcat gacactgaat gtggagtgga tgcccattca cacacgggcc tgcgtgggca ccttgattgg ctatgtctac agcctgggcc agttcctcct ggctggtgtg gcctacgctg tgccccactg gcgccacctg cagctactgg tctctgcgcc tttttttgcc ttcttcatct actcctggtt cttcattgag tcggcccgct ggcactcctc ctccgggagg ctggacctca ccctgagggc cctgcagaga gtcgcccgga tcaatgggaa gcgggaagaa ggagccaaat tgagtatgga ggtactccgg gccagtctgc agaaggagct gaccatgggc aaaggccagg catcggccat ggagctgctg cgctgcccca ccctccgcca cctcttcctc tgcctctcca tgctgtggtt tgccactagc tttgcatact atgggctggt catggacctg cagggctttg gagtcagcat ctacctaatc caggtgatct ttggtgctgt ggacctgcct gccaagcttg tgggcttcct tgtcatcaac tccctgggtc gccggcctgc ccagatggct gcactgctgc tggcaggcat ctgcatcctg ctcaatgggg tgatacccca ggaccagtcc attgtccgaa cctctcttgc tgtgctgggg aagggttgtc tggctgcctc cttcaactgc atcttcctgt atactgggga actgtatccc acaatgatcc ggcagacagg catgggaatg ggcagcacca tggcccgagt gggcagcatc gtgagcccac tggtgagcat gactgccgag ctctacccct ccatgcctct cttcatctac ggtgctgttc ctgtggccgc cagcgctgtc actgtcctcc tgccagagac cctgggccag ccactgccag acacggtgca ggacctggag agcaggaaag ggaaacagac gcgacagcaa caagagcacc agaagtatat ggtcccactg caggcctcag cacaagagaa gaatggactc Protein function: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1- propanesulfonic acid (DMPS). Mediates the sodium- independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2- furanpropionate (CMPF), cidofovir, adefovir, 9-(2- phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid. PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S- dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate. [The UniProt Consortium]