SLC16A1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC

Length: 1293 Sequence: ATGCCACCAG CAGTTGGAGG TCCAGTTGGA TACACCCCCC CAGATGGAGG CTGGGGCTGG GCAGTGGTAA TTGGAGCTTT CATTTCCATC GGCTTCTCTT ATGCATTTCC CAAATCAATT ACTGTCTTCT TCAAAGAGAT TGAAGGTATA TTCCATGCCA CCACCAGCGA AGTGTCATGG ATATCCTCCA TAATGTTGGC TGTCATGTAT GGTGGAGGTC CTATCAGCAG TATCCTGGTG AATAAATATG GAAGTCGTAT AGTCATGATT GTTGGTGGCT GCTTGTCAGG CTGTGGCTTG ATTGCAGCTT CTTTCTGTAA CACCGTACAG CAACTATACG TCTGTATTGG AGTCATTGGA GGTCTTGGGC TTGCCTTCAA CTTGAATCCA GCTCTGACCA TGATTGGCAA GTATTTCTAC AAGAGGCGAC CATTGGCCAA CGGACTGGCC ATGGCAGGCA GCCCTGTGTT CCTCTGTACT CTGGCCCCCC TCAATCAGGT TTTCTTCGGT ATCTTTGGAT GGAGAGGAAG CTTTCTAATT CTTGGGGGCT TGCTACTAAA CTGCTGTGTT GCTGGAGCCC TCATGCGACC AATCGGGCCC AAGCCAACCA AGGCAGGGAA AGATAAGTCT AAAGCATCCC TTGAGAAAGC TGGAAAATCT GGTGTGAAAA AAGATCTGCA TGATGCAAAT ACAGATCTTA TTGGAAGACA CCCTAAACAA GAGAAACGAT CAGTCTTCCA AACAATTAAT CAGTTCCTGG ACTTAACCCT ATTCACCCAC AGAGGCTTTT TGCTATACCT CTCTGGAAAT GTGATCATGT TTTTTGGACT CTTTGCACCT TTGGTGTTTC TTAGTAGTTA TGGGAAGAGT CAGCATTATT CTAGTGAGAA GTCTGCCTTC CTTCTTTCCA TTCTGGCTTT TGTTGACATG GTAGCCCGAC CATCTATGGG ACTTGTAGCC AACACAAAGC CAATAAGACC TCGAATTCAG TATTTCTTTG CGGCTTCCGT TGTTGCAAAT GGAGTGTGTC ATATGCTAGC ACCTTTATCC ACTACCTATG TTGGATTCTG TGTCTATGCG GGATTCTTTG GATTTGCCTT CGGGTGGCTC AGCTCCGTAT TGTTTGAAAC ATTGATGGAC CTTGTTGGAC CCCAGAGGTT CTCCAGCGCT GTGGGATTGG TGACCATTGT GGAATGCTGT CCTGTCCTCC TGGGGCCACC ACTTTTAGGT ATAGTATATC TCCCTACTAA TGTGGGTCTA TTACAAAACA AGCATGTAAG ATGGGAATGC Protein function: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. [The UniProt Consortium]