SETD6 (Vector pUC, Accession No. BC022451)

Length: 1422 Sequence: atggcgaccc aggcgaagcg tccacgggtg gcggggcccg tggacggcgg cgacctggat cctgtggcct gcttcctgag ctggtgccgg cgggtggggc tggagctgag tcccaaggtg agcgagcgag ccggcgggcg gaggacccgc ggcggggcgc gggctgccct gaccagccct cctgctcagg tggcggtcag ccggcagggc acggtggccg gctacggcat ggtggcccgg gagagcgtgc aggccggaga gttgctgttc gtggtgccgc gggccgcgct cctgtcgcag cacacctgct ccatcggcgg cctgctggag cgagagcgag ttgcgctgca gagccagtcg ggctgggtgc cactgctgct ggcgctgctc cacgagctgc aggccccggc ctcacgctgg aggccctact ttgcgctctg gcccgagctg ggccgcttgg agcacccgat gttctggcca gaggaggagc gccggtgcct gctccagggc acaggcgtac ctgaggccgt ggagaaggat ttggccaaca tcagcagcga gtaccagtcc atcgtgctgc ccttcatgga agcccacccc gatctcttca gcctcggggt tcgctcccta gaactctacc accagctggt ggcccttgtg atggcctata gctttcagga accactggag gaagaagagg atgaaaagga gcccaactcc cccgtgatgg tgcctgctgc agacatacta aaccacttag ccaatcacaa cgccaatcta gaatactctg cgaattgtct tcggatggta gccactcagc ccattcctaa aggccatgag attttcaaca cttatgggca aatggctaac tggcaactga ttcatatgta cggttttgtt gaaccatatc ctgacaacac agatgacaca gctgacattc agatggtgac agttcgtgag gcagcattac agggaacaaa aactgaagct gaaaggcacc tagtgtacga gcgctgggat ttcctatgca aactggagat ggtaggggaa gagggagcct ttgtgatagg gagggaggag gtgctgactg aagaggagct gaccaccaca ctaaaggtac tgtgcatgcc tgctgaggag ttcagagagc ttaaagacca ggatggaggg ggagatgata aaagggaaga gggcagcctg acgatcacaa atattcccaa gctcaaagca tcgtggagac agctgcttca aaacagtgtt ctactgactt tgcagaccta tgccacagac ttaaaaactg accaaggttt actcagtaat aaggaagtct atgcgaaact cagctggagg gaacagcaag ccttacaggt tcgctatggt cagaagatga tcttacatca gttgttggaa ctgacaagtt Protein function: Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF- kappa-B transcription factor activity (PubMed:21131967). Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal. [The UniProt Consortium]