PTPMT1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 606 Sequence: atggcggcca ccgcgctgct ggaggccggc ctggcgcggg tgctcttcta cccgacgctg ctctacaccc tgttccgcgg gaaggtgccg ggtcgggcgc accgggactg gtaccaccgc atcgacccca ccgtgctgct gggcgcgctg ccgttgcgga gcttgacgcg ccagctggta caggacgaga acgtgcgcgg ggtgatcacc atgaacgagg agtacgagac gaggttcctg tgcaactctt cacaggagtg gaagagacta ggagtcgagc agctgcggct cagcacagta gacatgactg ggatccccac cttggacaac ctccagaagg gagtccaatt tgctctcaag taccagtcgc tgggccagtg tgtttacgtg cattgtaagg ctgggcgctc caggagtgcc actatggtgg cagcatacct gattcaggtg cacaaatgga gtccagagga ggctgtaaga gccatcgcca agatccggtc atacatccac atcaggcctg gccagctgga tgttcttaaa gagttccaca agcagattac tgcacgggca acaaaggatg ggacttttgt catttcaaag Protein function: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity (PubMed:24709986). [The UniProt Consortium]