PSMB1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 726 Sequence: atgttgtcct ctacagccat gtattcggct gctggcagag acttggggat ggaaccgcac agagccgcgg gccctttgca gctgcgattt tcgccctacg ttttcaacgg aggtactata ctggcaattg ctggagaaga ttttgcaatt gttgcttctg atactcgatt gagtgaaggg ttttcaattc atacgcggga tagccccaaa tgttacaaat taacagacaa aacagtcatt ggatgcagcg gttttcatgg agactgtctt acgctgacaa agattattga agcaagacta aagatgtata agcattccaa taataaggcc atgactacgg gggcaattgc tgcaatgctg tctacaatcc tgtattcaag gcgcttcttt ccatactatg tttacaacat catcggtgga cttgatgaag aaggaaaggg ggctgtatac agctttgatc cagtagggtc ttaccagaga gactccttca aggctggagg ctcagcaagt gccatgctac agcccctgct tgacaaccag gttggtttta agaacatgca gaatgtggag catgttccgc tgtccttgga cagagccatg cggctggtga aagatgtctt catttctgcg gctgagagag atgtgtacac tggggacgca ctccggatct gcatagtgac caaagagggc atcagggagg aaactgtttc cttaaggaag Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). [The UniProt Consortium]