PSMA6 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 741 Sequence: atgtcccgtg gttccagcgc cggttttgac cgccacatta ccattttttc acccgagggt cggctctacc aagtagaata tgcttttaag gctattaacc agggtggcct tacatcagta gctgtcagag ggaaagactg tgcagtaatt gtcacacaga agaaagtacc tgacaaatta ttggattcca gcacagtgac tcacttattc aagataactg aaaacattgg ttgtgtgatg accggaatga cagctgacag cagatcccag gtacagaggg cacgctatga ggcagctaac tggaaataca agtatggcta tgagattcct gtggacatgc tgtgtaaaag aattgccgat atttctcagg tctacacaca gaatgctgaa atgaggcctc ttggttgttg tatgatttta attggtatag atgaagagca aggccctcag gtatataagt gtgatcctgc aggttactac tgtgggttta aagccactgc agcgggagtt aaacaaactg agtcaaccag cttccttgaa aaaaaagtga agaagaaatt tgattggaca tttgagcaga cagtggaaac tgcaattaca tgcctgtcta ctgttctatc aattgatttc aaaccttcag aaatagaagt tggagtagtg acagttgaaa atcctaaatt caggattctt acagaagcag agattgatgc tcaccttgtt gctctagcag agagagacta Protein function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin- independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). [The UniProt Consortium]