PBRM1 (Vector pUC, Accession No. BC129934)

Length: 4959 Sequence: ATGGGTTCCA AGAGAAGAAG AGCTACCTCC CCTTCCAGCA GTGTCAGCGG GGACTTTGAT GATGGGCACC ATTCTGTGTC AACACCAGGC CCAAGCAGGA AAAGGAGGAG ACTTTCCAAT CTTCCAACTG TAGATCCTAT TGCCGTGTGC CATGAACTCT ATAATACCAT CCGAGACTAT AAGGATGAAC AGGGCAGACT TCTCTGTGAG CTCTTCATTA GGGCACCAAA GCGAAGAAAT CAACCAGACT ATTATGAAGT GGTTTCTCAG CCCATTGACT TGATGAAAAT CCAACAGAAA CTAAAAATGG AAGAGTATGA TGATGTTAAT TTGCTGACTG CTGACTTCCA GCTTCTTTTT AACAATGCAA AGTCCTATTA TAAGCCAGAT TCTCCTGAAT ATAAAGCCGC TTGCAAACTC TGGGATTTGT ACCTTCGAAC AAGAAATGAG TTTGTTCAGA AAGGAGAAGC AGATGACGAA GATGATGATG AAGATGGGCA AGACAATCAG GGCACAGTGA CTGAAGGATC TTCTCCAGCT TACTTGAAGG AGATCCTGGA GCAGCTTCTT GAAGCCATAG TTGTAGCTAC AAATCCATCA GGACGTCTCA TTAGCGAACT TTTTCAGAAA CTGCCTTCTA AAGTGCAATA TCCAGATTAT TATGCAATAA TTAAGGAGCC TATAGATCTC AAGACCATTG CCCAGAGGAT ACAGAATGGA AGCTACAAAA GTATTCATGC AATGGCCAAA GATATAGATC TCCTCGCAAA AAATGCCAAA ACTTATAATG AGCCTGGCTC TCAAGTATTC AAGGATGCAA ATTCAATTAA AAAAATATTT TATATGAAAA AGGCTGAAAT TGAACATCAT GAAATGGCTA AGTCAAGTCT TCGAATGAGG ACTCCATCCA ACTTGGCTGC AGCCAGACTG ACAGGTCCTT CACACAGTAA AGGCAGCCTT GGTGAAGAGA GAAATCCCAC TAGCAAGTAT TACCGTAATA AAAGAGCAGT ACAAGGAGGT CGTTTATCAG CAATTACAAT GGCACTTCAA TATGGCTCAG AAAGTGAAGA AGATGCTGCT TTAGCTGCTG CACGCTATGA AGAGGGAGAG TCAGAAGCAG AAAGCATCAC TTCCTTTATG GATGTTTCAA ATCCTTTTTA TCAGCTTTAT GACACAGTTA GGAGTTGTCG GAATAACCAA GGGCAGCTAA TAGCTGAACC TTTTTACCAT TTGCCTTCAA AGAAAAAATA CCCTGATTAT TACCAGCAAA TTAAAATGCC CATATCACTA CAACAGATCC GAACAAAACT GAAGAATCAA GAATATGAAA CTTTAGATCA TTTGGAGTGT GATCTGAATT TAATGTTTGA AAATGCCAAA CGCTATAATG TGCCCAATTC AGCCATCTAC AAGCGAGTTC TAAAATTGCA GCAAGTTATG CAGGCAAAGA AGAAAGAGCT TGCCAGGAGA GACGATATCG AGGACGGAGA CAGCATGATC TCTTCAGCCA CCTCTGATAC TGGTAGTGCC AAAAGAAAAA GGAACACTCA TGACAGTGAG ATGTTGGGTC TCAGGAGGCT ATCCAGTAAA AAGAACATAA GAAAGCAGCG AATGAAAATC TTATTCAATG TTGTTCTTGA AGCTCGAGAG CCAGGTTCAG GCAGAAGACT TTGTGACCTA TTTATGGTTA AACCATCCAA AAAGGACTAT CCTGATTATT ATAAAATCAT CTTGGAGCCA ATGGACTTGA AAATAATTGA GCATAACATC CGCAATGACA AATATGCTGG TGAAGAGGGA ATGATAGAAG ACATGAAGCT GATGTTCCGG AATGCCAGGC ACTATAATGA GGAGGGCTCC CAGGTTTATA ATGATGCACA TATCCTGGAG AAGTTACTCA AGGAGAAAAG GAAAGAGCTG GGCCCACTGC CTGATGATGA TGACATGGCT TCTCCCAAAC TCAAGCTGAG TAGGAAGAGT GGCATTTCTC CTAAAAAATC AAAATACATG ACTCCAATGC AGCAGAAACT AAATGAGGTC TATGAAGCTG TAAAGAACTA TACTGATAAG AGGGGTCGCC GCCTCAGTGC CATATTTCTG AGGCTTCCCT CTAGATCTGA GTTGCCTGAC TACTATCTGA CTATTAAAAA GCCCATGGAC ATGGAAAAAA TTCGAAGTCA CATGATGGCC AACAAGTACC AAGATATTGA CTCTATGGTT GAGGACTTTG TCATGATGTT TAATAATGCC TGTACATACA ATGAGCCGGA GTCTTTGATC TACAAAGATG CTCTTGTTCT ACACAAAGTC CTGCTTGAAA CACGCAGAGA CCTGGAGGGA GATGAGGACT CTCATGTCCC AAATGTGACT TTGCTGATTC AAGAGCTTAT CCACAATCTT TTTGTGTCAG TCATGAGTCA TCAGGATGAT GAGGGAAGAT GCTACAGCGA TTCTTTAGCA GAAATTCCTG CTGTGGATCC CAACTTTCCT AACAAACCAC CCCTTACATT TGACATAATT AGGAAGAATG TTGAAAATAA TCGCTACCGT CGGCTTGATT TATTTCAAGA GCATATGTTT GAAGTATTGG AACGAGCAAG AAGGATGAAT CGGACAGATT CAGAAATATA TGAAGATGCA GTAGAACTTC AGCAGTTTTT TATTAAAATT CGTGATGAAC TCTGCAAAAA TGGAGAGATT CTTCTTTCAC CGGCACTCAG CTATACCACA AAACATTTGC ATAATGATGT GGAGAAAGAG AGAAAGGAAA AATTGCCAAA AGAAATAGAG GAAGATAAAC TAAAACGAGA AGAAGAAAAA AGAGAAGCTG AAAAGAGTGA AGATTCCTCT GGTGCTGCAG GCCTCTCAGG CTTACATCGC ACATACAGCC AGGACTGTAG CTTTAAAAAC AGCATGTACC ATGTTGGAGA TTACGTCTAT GTGGAACCTG CAGAGGCCAA CCTACAACCA CATATCGTCT GTATTGAAAG ACTGTGGGAG GATTCAGCTG GTGAAAAATG GTTGTATGGC TGTTGGTTTT ACCGACCAAA TGAAACATTC CACCTGGCTA CACGAAAATT TCTAGAAAAA GAAGTTTTTA AGAGTGACTA TTACAACAAA GTTCCAGTTA GTAAAATTCT AGGCAAGTGT GTGGTCATGT TTGTCAAGGA ATACTTTAAG TTATGCCCAG AAAACTTCCG AGATGAGGAT GTTTTTGTCT GTGAATCACG GTATTCTGCC AAAACCAAAT CTTTTAAGAA AATTAAACTG TGGACCATGC CCATCAGCTC AGTCAGGTTT GTCCCTCGGG ATGTGCCTCT GCCTGTGGTT CGCGTGGCCT CTGTATTTGC AAATGCAGAT AAAGGTGATG ATGAGAAGAA TACAGACAAC TCAGAGGACA GTCGAGCTGA AGACAATTTT AACTTGGAAA AGGAAAAAGA AGATGTCCCT GTGGAAATGT CCAATGGTGA ACCAGGTTGC CACTACTTTG AGCAGCTCCA TTACAATGAC ATGTGGCTGA AGGTTGGCGA CTGTGTCTTC ATCAAGTCCC ATGGCCTGGT GCGTCCTCGT GTGGGCAGAA TTGAAAAAGT ATGGGTTCGA GATGGAGCTG CATATTTTTA TGGCCCCATC TTCATTCACC CAGAAGAAAC AGAGCATGAG CCCACAAAAA TGTTCTACAA AAAAGAAGTA TTTCTGAGTA ATCTGGAAGA AACCTGCCCC ATGACATGTA TTCTCGGAAA GTGTGCTGTG TTGTCATTCA AGGACTTCCT CTCCTGCAGG CCAACTGAAA TACCAGAAAA TGACATTCTG CTTTGTGAGA GCCGCTACAA TGAGAGCGAC AAGCAGATGA AGAAATTCAA AGGATTGAAG AGGTTTTCAC TCTCTGCTAA AGTGGTAGAT GATGAAATTT ACTACTTCAG AAAACCAATT GTTCCTCAGA AGGAGCCATC ACCTTTGCTG GAAAAGAAGA TCCAGTTGCT AGAAGCTAAA TTTGCCGAGT TAGAAGGTGG AGATGATGAT ATTGAAGAGA TGGGAGAAGA AGATAGTGAG GTCATTGAAC CTCCTTCTCT ACCTCAGCTT CAGACCCCCC TGGCCAGTGA GCTGGACCTC ATGCCCTACA CACCCCCACA GTCTACCCCA AAGTCTGCCA AAGGCAGTGC AAAGAAGGAA GGCTCCAAAC GGAAAATCAA CATGAGTGGC TACATCCTGT TCAGCAGTGA GATGAGGGCT GTGATTAAGG CCCAACACCC AGACTACTCT TTCGGGGAGC TCAGCCGCCT GGTGGGGACA GAATGGAGAA ATCTTGAGAC AGCCAAGAAA GCAGAATATG AAGAGCGGGC AGCTAAAGTT GCTGAGCAGC AGGAGAGAGA GCGAGCAGCA CAGCAACAGC AGCCGAGTGC TTCTCCCCGA GCAGGCACCC CTGTGGGGGC TCTCATGGGG GTGGTGCCAC CACCAACACC AATGGGGATG CTCAATCAGC AGTTGACACC TGTTGCAGGT GTGATGAACC AAGGAGTGGC CCCTATGGTA GGGACTCCAG CACCAGGTGG AAGTCCATAT GGACAACAGG TGGGAGTTTT GGGGCCTCCA GGGCAGCAGG CACCACCTCC ATATCCCGGC CCACATCCAG CTGGACCCCC TGTCATACAG CAGCCAACAA CACCCATGTT TGTAGCTCCC CCACCAAAGA CCCAGCGGCT TCTTCACTCA GAGGCCTACC TGAAATACAT TGAAGGACTC AGTGCGGAGT CCAACAGCAT TAGCAAGTGG GATCAGACAC TGGCAGCTCG AAGACGCGAC GTCCATTTGT CGAAAGAACA GGAGAGCCGC CTACCCTCTC ACTGGCTGAA AAGCAAAGGG GCCCACACCA CCATGGCAGA TGCCCTCTGG CGCCTTCGAG ATTTGATGCT CCGGGACACC CTCAACATTC GCCAAGCATA CAACCTAGAA Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. [The UniProt Consortium]