PAAF1 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1179 Sequence: atggcggcgc ctttgaggat tcagagcgac tgggcgcaag ccctcaggaa ggatgaaggg gaggcctggc tgagctgtca tcccccaggg aaaccatctt tgtatggcag cctgacttgt caaggaattg gcctagatgg catcccagag gttacagctt cagaaggatt tactgtgaat gaaataaaca agaaaagcat tcatatttca tgtccaaagg aaaatgcatc ttctaagttt ttggcaccat atactacttt ttccagaatt catacaaaga gtataacatg cctggacatt tccagcagag gaggtcttgg tgtgtcttct agtactgacg ggaccatgaa aatctggcag gcttccaatg gagaactcag gagagtattg gaaggacatg tgtttgatgt gaattgttgc aggtttttcc catcaggcct tgtggtcctg agtgggggaa tggatgccca gctgaagata tggtcagctg aagatgctag ctgcgtggtg accttcaaag gtcacaaagg aggtatcctg gatacagcca tcgttgatcg ggggaggaat gtggtgtctg cttctcgaga tgggacagca cgactttggg attgtgggcg ctcaggctgc ttgggagtcc ttgcagattg tggttcttct atcaatggag tggcggtggg tgctgctgac aactccataa accttggctc ccctgagcag atgcccagtg aacgggaggt tggaacagag gccaaaatgc tgctcttggc ccgggaagat aagaaacttc agtgcttggg actacagagc aggcagctgg tgttcctctt tattggctca gacgctttca actgctgtac ttttctctct ggcttcttgc tattggctgg gactcaagat ggaaacattt atcagctgga tgtgaggagt ccaagggctc cggtacaagt catccacaga tcaggagcac cagttctatc cctgctaagt gtcagagatg gattcattgc tagccaaggt gatggaagct gttttattgt ccagcaagac ttagactatg tcactgagct cactggggct gactgtgacc ctgtgtacaa ggtagccaca tgggagaagc agatctacac atgctgtcga gacggtcttg tacgacgcta ccagctttct Protein function: Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation. [The UniProt Consortium]