NRCAM (Vector pUC, Accession No. BC115736)

Length: 3579 Sequence: ATGCAGCTTA AAATAATGCC GAAAAAGAAG CGCTTATCTG CGGGCAGAGT GCCCCTGATT CTCTTCCTGT GCCAGATGAT TAGTGCACTG GAAGTACCTC TTGATCCAAA ACTTCTTGAA GACTTGGTAC AGCCTCCAAC CATCACCCAA CAGTCTCCAA AAGATTACAT TATTGACCCT CGGGAGAATA TTGTAATCCA GTGTGAAGCC AAAGGGAAAC CGCCCCCAAG CTTTTCCTGG ACCCGTAATG GGACTCATTT TGACATCGAT AAAGACCCTC TGGTCACCAT GAAGCCTGGC ACAGGAACGC TCATAATTAA CATCATGAGC GAAGGGAAAG CTGAGACCTA TGAAGGAGTC TATCAGTGTA CAGCAAGGAA CGAACGCGGA GCTGCAGTTT CTAATAACAT TGTTGTCCGC CCATCCAGAT CACCATTGTG GACCAAAGAA AAACTTGAAC CAATCACACT TCAAAGTGGT CAGTCTTTAG TACTTCCCTG CAGACCCCCA ATTGGATTAC CACCACCTAT AATATTTTGG ATGGATAATT CCTTTCAAAG ACTTCCACAA AGTGAGAGAG TTTCTCAAGG TTTGAATGGG GACCTTTATT TTTCCAATGT CCTCCCAGAG GACACCCGCG AAGACTATAT CTGTTATGCT AGATTTAATC ATACTCAAAC CATACAGCAG AAGCAACCTA TTTCTGTGAA GGTGATTTCA GCTAAATCAA GTAGAGAGAG GCCACCAACA TTTTTAACTC CAGAAGGCAA TGCAAGTAAC AAAGAGGAAT TAAGAGGAAA TGTGCTTTCA CTGGAGTGCA TTGCAGAAGG ACTGCCTACC CCAATTATTT ACTGGGCAAA GGAAGATGGA ATGCTACCCA AAAACAGGAC AGTTTATAAG AACTTTGAGA AAACCTTGCA GATCATTCAT GTTTCAGAAG CAGACTCTGG AAATTACCAA TGTATAGCAA AAAATGCATT AGGAGCCATC CACCATACCA TTTCTGTTAG AGTTAAAGCG GCTCCATACT GGATCACAGC CCCTCAAAAT CTTGTGCTGT CCCCAGGAGA GGATGGGACC TTGATCTGCA GAGCTAATGG CAACCCCAAA CCCAGAATTA GCTGGTTAAC AAATGGAGTC CCAATAGAAA TTGCCCCTGA TGACCCCAGC AGAAAAATAG ATGGCGATAC CATTATTTTT TCAAATGTTC AAGAAAGATC AAGTGCAGTA TATCAGTGCA ATGCCTCTAA TGAATATGGA TATTTACTGG CAAACGCATT TGTAAATGTG CTGGCTGAGC CACCACGAAT CCTCACACCT GCAAACACAC TCTACCAGGT CATTGCAAAC AGGCCTGCTT TACTAGACTG TGCCTTCTTT GGGTCTCCTC TCCCAACCAT CGAGTGGTTT AAAGGAGCTA AAGGAAGTGC TCTTCATGAA GATATTTATG TTTTACATGA AAATGGAACT TTGGAAATTC CTGTGGCCCA AAAGGACAGT ACAGGAACTT ATACGTGTGT TGCAAGGAAT AAATTAGGGA TGGCAAAGAA TGAAGTTCAC TTAGAAATCA AAGATGCTAC ATGGATCGTT AAACAGCCCG AATATGCAGT TGTGCAAAGA GGGAGCATGG TGTCCTTTGA ATGCAAAGTG AAACATGATC ACACCTTATC CCTCACTGTC CTGTGGCTGA AGGACAACAG GGAACTGCCC AGTGATGAAA GGTTCACTGT TGACAAGGAT CATCTAGTGG TAGCTGATGT CAGTGACGAT GACAGCGGGA CCTACACGTG TGTGGCCAAC ACCACTCTGG ACAGCGTCTC CGCCAGCGCT GTGCTTAGCG TTGTTGCTCC TACTCCAACT CCAGCTCCCG TTTACGATGT CCCAAATCCT CCCTTTGACT TAGAACTGAC AGATCAACTT GACAAAAGTG TTCAGCTGTC ATGGACCCCA GGCGATGACA ACAATAGCCC CATTACAAAA TTCATCATCG AATATGAAGA TGCAATGCAC AAGCCAGGGC TGTGGCACCA CCAAACTGAA GTTTCTGGAA CACAGACCAC AGCCCAGCTG AAGCTGTCTC CTTACGTGAA CTACTCCTTC CGCGTGATGG CAGTGAACAG CATTGGGAAG AGCTTGCCCA GCGAGGCCTC TGAGCAGTAT TTGACGAAAG CCTCAGAACC AGATAAAAAC CCCACAGCTG TGGAAGGACT GGGATCAGAG CCTGATAATT TGGTGATTAC GTGGAAGCCC TTGAATGGTT TCGAATCTAA TGGGCCAGGC CTTCAGTACA AAGTTAGCTG GCGCCAGAAA GATGGTGATG ATGAATGGAC ATCTGTGGTT GTGGCAAATG TATCCAAATA TATTGTCTCA GGCACGCCAA CCTTTGTTCC ATACCTGATC AAAGTTCAGG CCCTGAATGA CATGGGGTTT GCCCCCGAGC CAGCTGTAGT CATGGGACAT TCTGGAGAAG ACCTCCCAAT GGTGGCTCCT GGGAACGTGC GTGTGAATGT GGTGAACAGT ACCTTAGCCG AGGTGCACTG GGACCCAGTA CCTCTGAAAA GCATCCGAGG ACACCTACAA GGCTATCGGA TTTACTATTG GAAGACCCAG AGTTCATCTA AAAGAAACAG ACGTCACATT GAGAAAAAGA TCCTCACCTT CCAAGGCAGC AAGACTCATG GCATGTTGCC GGGGCTAGAG CCCTTTAGCC ACTACACACT GAATGTCCGA GTGGTCAATG GGAAAGGGGA GGGCCCAGCC AGCCCTGACA GAGTCTTTAA TACTCCAGAA GGAGTCCCCA GTGCTCCCTC GTCTTTGAAG ATTGTGAATC CAACACTGGA CTCTCTCACT TTGGAATGGG ATCCACCGAG CCACCCGAAT GGCATTTTGA CAGAGTACAC CTTAAAGTAT CAGCCAATTA ACAGCACACA TGAATTAGGC CCTCTGGTAG ATTTGAAAAT TCCTGCCAAC AAGACACGGT GGACTTTAAA AAATTTAAAT TTCAGCACTC GATATAAGTT TTATTTCTAT GCACAAACAT CAGCAGGATC AGGAAGTCAA ATTACAGAGG AAGCAGTAAC AACTGTGGAT GAAGCTGGTA TTCTTCCACC TGATGTAGGT GCAGGCAAAG CGATGGCAAG CCGGCAGGTG GATATTGCAA CTCAGGGCTG GTTCATTGGT CTGATGTGTG CTGTTGCTCT CCTTATCTTA ATTTTGCTGA TTGTTTGCTT CATCAGAAGA AACAAGGGTG GTAAATATCC AGTTAAAGAA AAGGAAGATG CCCATGCTGA CCCTGAAATC CAGCCTATGA AGGAAGATGA TGGGACATTT GGAGAATACA GTGATGCAGA AGACCACAAG CCTTTGAAAA AAGGAAGTCG AACTCCTTCA GACAGGACTG TGAAAAAAGA AGATAGTGAC GACAGCCTAG TTGACTATGG AGAAGGGGTT AATGGCCAGT TCAATGAGGA TGGCTCCTTT ATTGGACAAT ACAGTGGTAA GAAAGAGAAA GAGCCGGCTG AAGGAAACGA AAGCTCAGAG GCACCTTCTC CTGTCAACGC CATGAATTCC Protein function: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes, not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier. [The UniProt Consortium]