IFT57 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1290 Sequence: atgactgctg ctctggccgt cgtcacgacg tcgggtttgg aagatggggt gcctaggtcc cgtggcgaag ggaccgggga agtggtcttg gagcgggggc ccggcgcggc ctaccacatg ttcgtggtga tggaggactt ggtggagaag ctgaagctgc tccgctacga ggaggagttc ctccggaaga gcaacctgaa ggccccgtcc agacactatt ttgcactgcc taccaaccct ggcgaacagt tctacatgtt ttgtactctt gctgcttggt tgattaataa agcgggacgt ccctttgagc agcctcaaga atatgatgac cctaatgcaa caatatctaa catactatcc gagcttcggt catttggaag aactgcagat tttcctcctt caaaattaaa gtcaggttat ggagaacatg tatgctatgt tcttgattgc ttcgctgaag aagcattgaa atatattggt ttcacctgga aaaggccaat atacccagta gaagaattag aagaagaaag cgttgcagaa gatgatgcag aattaacatt aaataaagtg gatgaagaat ttgtggaaga agagacagat aatgaagaaa actttattga tctcaacgtt ttaaaggccc agacatatca cttggatatg aacgagactg ccaaacaaga agatattttg gaatccacaa cagatgctgc agaatggagc ctagaagtgg aacgtgtact accgcaactg aaagtcacga ttaggactga caataaggat tggagaatcc atgttgacca aatgcaccag cacagaagtg gaattgaatc tgctctaaag gagaccaagg gatttttgga caaactccat aatgaaatta ctaggacttt ggaaaagatc agcagccgag aaaagtacat caacaatcag cttgagaatt tggttcaaga atatcgtgca gctcaagccc agctgagtga ggcaaaggag cgataccagc agggaaatgg aggagtgacg gaaagaacca gactcctctc tgaggttatg gaagaattag aaaaggtaaa acaagaaatg gaagaaaagg gcagcagcat gactgatggt gctcctttgg tgaagattaa acagagctta acaaaactga agcaagaaac tgtagagatg gacattagaa ttggcattgt ggaacacaca ctactccaat caaagctgaa ggagaagtcc aacatgacta ggaacatgca tgccacagtt attccagaac cagcaacagg Protein function: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'- AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear. [The UniProt Consortium]