HIST2H2BE (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or p

Length: 381 Sequence: ATGCCTGAAC CTGCTAAGTC CGCTCCGGCC CCTAAAAAGG GCTCCAAGAA AGCCGTCACC AAAGCCCAGA AGAAAGACGG CAAGAAGCGC AAGCGCAGCC GCAAAGAGAG CTACTCCATC TACGTGTACA AGGTGCTGAA GCAGGTCCAC CCCGACACCG GCATCTCGTC CAAGGCCATG GGCATCATGA ACTCCTTCGT CAACGACATC TTCGAGCGCA TCGCGGGAGA GGCTTCCCGC CTGGCGCACT ACAACAAGCG CTCCACCATC ACATCCCGCG AGATCCAGAC GGCCGTGCGC CTGCTGCTGC CCGGCGAGCT GGCCAAGCAC GCCGTGTCCG AGGGCACCAA GGCGGTCACC AAGTACACCA GCTCCAAGTG Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]