GLRA3 (Vector pENTR223.1, Accession No. BC036086)

Length: 1395 Sequence: atggcccacg tgagacactt tcggacatta gtttcgggat tttacttctg ggaagcagca ctgttactca gtttggttgc cacaaaggaa acagacagtg caagatctcg aagtgctcca atgtcacctt ctgattttct ggataaatta atgggcagga catcaggata tgatgcaaga atcagaccca attttaaagg ccctccagtt aatgtcacat gcaacatatt catcaacagc tttggctcta tcgcagagac gaccatggat tacagagtga atatctttct tcgtcagaaa tggaatgatc cccgcctcgc gtacagtgaa tatcctgacg actctttaga cctcgacccc tccatgttgg actccatttg gaaacctgat ttgttctttg ccaatgaaaa gggtgccaac tttcatgaag tcactacaga caacaaattg ctaagaattt tcaaaaatgg aaatgttctt tattcaataa gattaacatt aacactttcc tgtccaatgg atctcaagaa ttttcccatg gatgtacaaa catgtataat gcaactggaa agctttgggt acacaatgaa tgatctcatt tttgaatggc aagatgaggc acccgtacaa gtggcagaag gactcacttt gccccagttt ctgttgaaag aagaaaaaga tttacgatac tgcactaaac attacaatac aggaaagttt acgtgtatag aagtgcgatt ccatctggag cgacaaatgg gatactatct gatccagatg tacattccca gtctcctgat tgttattcta tcctgggttt cgttctggat caacatggat gcagcaccgg ccagggtagc tctggggata accaccgtgc taacgatgac tacacagagt tcaggatcac gagcttcctt gccaaaagtt tcatatgtca aagctattga tatttggatg gcagtatgcc tcctttttgt gttttcagca cttctggagt atgcagctgt aaattttgta tcaagacaac acaaagaact tctgagattt cgacgaaaga gaaagaataa gacagaagcc tttgcactgg agaagtttta ccgtttctca gatatggatg atgaggtaag ggaaagccga ttcagcttca cagcctatgg aatgggacca tgtctacaag caaaggatgg catgactcca aagggcccca accaccctgt ccaggtaatg ccaaaaagtc ctgatgaaat gaggaaggtc tttatcgacc gggccaagaa gattgatacc atctcccgag cctgcttccc attagctttt ttgattttta atattttcta ctgggttatc tataaaattc ttaggcatga ggatattcat cagcagcaag Protein function: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition, heteropentameric channels display faster channel closure. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Contributes to increased pain perception in response to increased prostaglandin E2 levels. Plays a role in cellular responses to ethanol. [The UniProt Consortium]