GABRB2 (Vector Vector will be determined during the manufacturing process, either pENTR223.1 or pUC,

Length: 1425 Sequence: ATGTGGAGAG TGCGGAAAAG GGGCTACTTT GGGATTTGGT CCTTCCCCTT AATAATCGCC GCTGTCTGTG CGCAGAGTGT CAATGACCCT AGTAATATGT CGCTGGTTAA AGAGACGGTG GATAGACTCC TGAAAGGCTA TGACATTCGT CTGAGACCAG ATTTTGGAGG TCCCCCCGTG GCTGTGGGGA TGAACATTGA CATTGCCAGC ATCGATATGG TTTCTGAAGT CAATATGGAT TATACCTTGA CAATGTACTT TCAACAAGCC TGGAGAGATA AGAGGCTGTC CTATAATGTA ATACCTTTAA ACTTGACTCT GGACAACAGA GTGGCAGACC AGCTCTGGGT GCCTGATACC TATTTCCTGA ACGATAAGAA GTCATTTGTG CACGGAGTGA CTGTTAAGAA CCGCATGATT CGCCTGCATC CTGATGGCAC CGTCCTTTAT GGACTCAGAA TCACAACCAC AGCTGCCTGC ATGATGGACC TAAGGAGGTA CCCACTGGAT GAACAAAACT GCACCTTGGA AATTGAGAGC TATGGATACA CAACTGATGA CATTGAGTTT TACTGGCGTG GCGATGATAA TGCAGTAACA GGAGTAACGA AAATTGAACT TCCACAGTTC TCTATTGTAG ATTACAAACT TATCACCAAG AAGGTTGTTT TTTCCACAGG TTCCTATCCC AGGTTATCCC TCAGCTTTAA GCTTAAGAGA AACATTGGCT ACTTTATCCT GCAAACATAC ATGCCTTCCA TCCTGATTAC CATCCTCTCC TGGGTCTCCT TCTGGATTAA TTACGATGCT TCAGCTGCAA GGGTGGCATT AGGAATCACA ACTGTCCTCA CAATGACCAC AATCAACACC CACCTCCGGG AAACTCTCCC TAAAATCCCC TATGTGAAGG CCATTGACAT GTACCTGATG GGGTGCTTTG TCTTCGTTTT CATGGCCCTT CTGGAATATG CCCTAGTCAA CTACATCTTC TTTGGGAGGG GGCCCCAACG CCAAAAGAAA GCAGCTGAGA AGGCTGCCAG TGCCAACAAT GAGAAGATGC GCCTGGATGT CAACAAGATG GACCCCCATG AGAACATCTT ACTGAGCACT CTCGAGATAA AAAATGAAAT GGCCACATCT GAGGCTGTGA TGGGACTTGG AGACCCCAGA AGCACAATGC TAGCCTATGA TGCCTCCAGC ATCCAGTATC GGAAAGCTGG GTTGCCCAGG CATAGTTTTG GCCGAAATGC TCTGGAACGA CATGTGGCGC AAAAGAAAAG TCGCCTGAGG AGACGCGCCT CCCAACTGAA AATCACCATC CCTGACTTGA CTGATGTGAA TGCCATAGAT CGGTGGTCCC GCATATTCTT CCCAGTGGTT TTTTCCTTCT TCAACATCGT CTATTGGCTT TATTATGTGA Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:8264558, PubMed:19763268, PubMed:27789573, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium]