CD320 (Vector pUC, Accession No. BC000668)

Length: 849 Sequence: atgagcggcg gttggatggc gcaggttgga gcgtggcgaa caggggctct gggcctggcg ctgctgctgc tgctcggcct cggactaggc ctggaggccg ccgcgagccc gctttccacc ccgacctctg cccaggccgc aggccccagc tcaggctcgt gcccacccac caagttccag tgccgcacca gtggcttatg cgtgcccctc acctggcgct gcgacaggga cttggactgc agcgatggca gcgatgagga ggagtgcagg attgagccat gtacccagaa agggcaatgc ccaccgcccc ctggcctccc ctgcccctgc accggcgtca gtgactgctc tgggggaact gacaagaaac tgcgcaactg cagccgcctg gcctgcctag caggcgagct ccgttgcacg ctgagcgatg actgcattcc actcacgtgg cgctgcgacg gccacccaga ctgtcccgac tccagcgacg agctcggctg tggaaccaat gagatcctcc cggaagggga tgccacaacc atggggcccc ctgtgaccct ggagagtgtc acctctctca ggaatgccac aaccatgggg ccccctgtga ccctggagag tgtcccctct gtcgggaatg ccacatcctc ctctgccgga gaccagtctg gaagcccaac tgcctatggg gttattgcag ctgctgcggt gctcagtgca agcctggtca ccgccaccct cctccttttg tcctggctcc gagcccagga gcgcctccgc ccactggggt tactggtggc catgaaggag tccctgctgc tgtcagaaca gaagacctcg Protein function: Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimuli, promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed:11418631). CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed:11418631). [The UniProt Consortium]