CALM1 (Vector pENTR223.1, Accession No. BC000454)

Length: 450 Sequence: atggctgatc agctgaccga agaacagatt gctgaattca aggaagcctt ctccctattt gataaagatg gcgatggcac catcacaaca aaggaacttg gaactgtcat gaggtcactg ggtcagaacc caacagaagc tgaattgcag gatatgatca atgaagtgga tgctgatggt aatggcacca ttgacttccc cgaatttttg actatgatgg ctagaaaaat gaaagataca gatagtgaag aagaaatccg tgaggcattc cgagtctttg acaaggatgg caatggttat atcagtgcag cagaactacg tcacgtcatg acaaacttag gagaaaaact aacagatgaa gaagtagatg aaatgatcag agaagcagat attgatggag acggacaagt caactatgaa gaattcgtac agatgatgac Protein function: Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Is a regulator of voltage-dependent L-type calcium channels (PubMed:31454269). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752). Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696). Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding (PubMed:25441029). [The UniProt Consortium]