ADIPOR2 (Vector pENTR223.1, Accession No. BC051858)

Length: 1161 Sequence: atgaacgagc caacagaaaa ccgattgggg tgcagcagga ctccagagcc agatataagg ctcagaaaag ggcaccaact ggatggtaca cgaagaggtg ataatgacag ccaccaagga gatttggagc ccattttaga ggcatctgtt ctatcttccc atcataaaaa aagctctgag gaacatgaat acagtgatga agctcctcag gaagatgagg gctttatggg catgtcccct ctcttacaag cccatcatgc tatggaaaaa atggaagaat ttgtttgtaa ggtatgggaa ggtcggtggc gagtgatccc tcatgatgta ctaccagact ggctcaagga taatgacttc ctcttgcatg gacaccggcc tcctatgcct tctttccggg cctgttttaa gagcattttc agaatacaca cagaaacagg caacatttgg acacatctct taggttgtgt attcttcctg tgcctgggga tcttttatat gtttcgccca aatatctcct ttgtggcccc tctgcaagag aaggtggtct ttggattatt tttcttagga gccattctct gcctttcttt ttcatggctc ttccacacag tctactgcca ctcagagggg gtctctcggc tcttctctaa actggattac tctggtattg ctcttctgat tatgggaagt tttgttcctt ggctttatta ttctttctac tgtaatccac aaccttgctt catctacttg attgtcatct gtgtgctggg cattgcagcc attatagtct cccagtggga catgtttgcc acccctcagt atcggggagt aagagcagga gtgtttttgg gcctaggcct gagtggaatc attcctacct tgcactatgt catctcggag gggttcctta aggccgccac catagggcag ataggctggt tgatgctgat ggccagcctc tacatcacag gagctgccct gtatgctgcc cggatccccg aacgcttttt ccctggcaaa tgtgacatct ggtttcactc tcatcagctg tttcatatct ttgtggttgc tggagctttt gttcacttcc atggtgtctc aaacctccag gagtttcgtt tcatgatcgg cgggggctgc agtgaagagg atgcactgtg Protein function: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. [The UniProt Consortium]