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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay39815-500 | 500 µg | - |
6 - 10 business days* |
135.00€
|
|||
Cay39815-1 | 1 mg | - |
6 - 10 business days* |
244.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Betaxolol-d7 is intended for use as an internal standard for the quantification of betaxolol... more
Product information "Betaxolol-d7 (hydrochloride)"
Betaxolol-d7 is intended for use as an internal standard for the quantification of betaxolol (Cay-18625) by GC- or LC-MS. Betaxolol is an antagonist of the beta1-adrenergic receptor (beta1-AR, Ki = 23 nM). It is selective for the beta1-AR over the beta2-AR (Ki = 790 nM). Betaxolol is cytotoxic to 10.014 pRSV-T human corneal epithelial cells. It reduces intraocular pressure in cynomolgus monkeys with ocular hypertension induced by laser trabeculoplasty when administered at a dose of 150 µg/animal. Betaxolol also inhibits sodium influx induced by the neurotoxin veratridine in rat cortical synaptosomes (IC50 = 28.3 µM).Formal Name: 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((propan-2-yl-d7)amino)propan-2-ol, monohydrochloride. CAS Number: 1219802-92-2. Molecular Formula: C18H22D7NO3 . HCl. Formula Weight: 350.9. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly soluble, Methanol: Slightly soluble, Water: Slightly soluble. SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NCC(O)COC1=CC=C(C=C1)CCOCC2CC2.Cl. InChi Code: InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16,/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3,1H/i1D3,2D3,14D,. InChi Key: CHDPSNLJFOQTRK-LBRFFFIWSA-N.
Keywords: | 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((propan-2-yl-d7)amino)propan-2-ol, monohydrochloride |
Supplier: | Cayman Chemical |
Supplier-Nr: | 39815 |
Properties
Application: | GC-MS, LC-MS, internal standard, quantification, adrenergic receptor beta-1 antagonist |
MW: | 350.9 D |
Formula: | C18H22D7NO3 . HCl |
Purity: | >99% deuterated forms (d1-d7) |
Format: | Solid |
Database Information
CAS : | 1219802-92-2| Matching products |
KEGG ID : | K04141 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H302 |
P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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