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Zymosan A is a glucan derived from the cell wall of S. cerevisiae that activates toll-like receptor 2 (TLR2) and a C-type lectin, dectin-1, on macrophages, monocytes, and dendritic cells to induce inflammatory signaling. It is commonly used to stimulate a sterile inflammatory response in mouse models of sepsis, shock, and peritonitis. In a mouse model of sepsis/shock, a lethal dose of zymosan A (500 mg/kg) in rats induced inflammation and shock leading to death. Zymosan A can also induce biosynthesis of eicosanoids.CAS Number: 58856-93-2. Formulation: (Request formulation change), A powder. Solubility: Chloroform: 100 µg/ml, DMSO: 200 µg/ml, Ethanol: 100 µg/ml.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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