YSK05

YSK05
Lipid-based Drug Delivery Tools
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay35786-5 5 mg -

6 - 10 business days*

101.00€
Cay35786-10 10 mg -

6 - 10 business days*

131.00€
Cay35786-25 25 mg -

6 - 10 business days*

276.00€
 
YSK05 is an ionizable cationic amino lipid (apparent pKa = ~6.5) that has been used in... more
Product information "YSK05"
YSK05 is an ionizable cationic amino lipid (apparent pKa = ~6.5) that has been used in combination with other lipids in the formation of liposomes and lipid nanoparticles (LNPs). Administration of cyclic di-GMP (Cay-17144) in YSK05-containing liposomes increases serum levels of IFN-beta, IFN-gamma, IL-6, and TNF-alpha and activates natural killer (NK) cells in mice, as well as decreases lung metastasis in a B16/F10 murine melanoma model of metastasis. Intravenous administration of factor VII siRNA in YSK05-containing LNPs reduces factor VII activity in isolated mouse plasma.Formal Name: 1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-piperidine. CAS Number: 1318793-78-0. Molecular Formula: C42H77NO2. Formula Weight: 628.1. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 25 mg/ml. SMILES: CCCCC/C=C\C/C=C\CCCCCCCCOC1(CCN(CC1)C)OCCCCCCCC/C=C\C/C=C\CCCCC. InChi Code: InChI=1S/C42H77NO2/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-40-44-42(36-38-43(3)39-37-42)45-41-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h12-15,18-21H,4-11,16-17,22-41H2,1-3H3/b14-12-,15-13-,20-18-,21-19-. InChi Key: KURBRAZBXURPCJ-QYCRHRGJSA-N.
Keywords: 1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-piperidine
Supplier: Cayman Chemical
Supplier-Nr: 35786

Properties

Application: Ionizable amino lipid, LNP formation
MW: 628.1 D
Formula: C42H77NO2
Purity: >90%
Format: Solution

Database Information

CAS : 1318793-78-0| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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