Thielavin A

Thielavin A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay21767-500 500 µg -

6 - 10 business days*

390.00€
Cay21767-2.5 2500 µg -

6 - 10 business days*

1,854.00€
 
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to... more
Product information "Thielavin A"
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B (Cay-18770). Thielavin A inhibits COX, blocking both the conversion of arachidonic acid (Cay-90010) to prostaglandin H2 (PGH2, Cay-17020) and the conversion of PGH2 to PGE2 (Cay-14010, IC50s = 10 and 40 µM, respectively). Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 µM). It is a non-competitive inhibitor of alpha-glucosidase from S. cerevisiae (IC50 = 23.8 µM, Ki = 27.8 µM).Formal Name: 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-benzoic acid, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester. CAS Number: 71950-66-8. Molecular Formula: C29H30O10. Formula Weight: 538.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: souble, DMSO: souble, Ethanol: soluble. SMILES: CC1=C(O)C=C(C)C(C(OC2=C(C)C(C)=C(C(OC3=C(C)C(C)=C(C(O)=O)C(O)=C3C)=O)C(O)=C2C)=O)=C1O. InChi Code: InChI=1S/C29H30O10/c1-10-9-18(30)15(6)22(31)19(10)28(36)38-26-14(5)12(3)21(24(33)17(26)8)29(37)39-25-13(4)11(2)20(27(34)35)23(32)16(25)7/h9,30-33H,1-8H3,(H,34,35). InChi Key: MGGMNKJGDSNTKZ-UHFFFAOYSA-N. Origin: Fungus/Unidentified sp..
Keywords: 4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-hydroxy-3,5,6-trimethyl-benzoic acid, 4-carboxy-3-hydroxy-2,5,6-trimethylphenyl ester
Supplier: Cayman Chemical
Supplier-Nr: 21767

Properties

Application: Fungal metabolite, COX inhibitor
MW: 538.5 D
Formula: C29H30O10
Purity: >95%
Format: Solid

Database Information

CAS : 71950-66-8| Matching products
KEGG ID : K11987 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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