Sphingosine (d14:1)

Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 0.0102 ng/ml. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate (PMA, Cay-10008014) in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 µM, respectively). [Matreya, LLC. Catalog No. 1833]Formal Name: 2S-amino-4E-tetradecene-1,3R-diol. CAS Number: 24558-60-9. Synonyms: D-erythro-Sphingosine C14. Molecular Formula: C14H29NO2. Formula Weight: 243.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: OC[C@H](N)[C@H](O)/C=C/CCCCCCCCC. InChi Code: InChI=1S/C14H29NO2/c1-2-3-4-5-6-7-8-9-10-11-14(17)13(15)12-16/h10-11,13-14,16-17H,2-9,12,15H2,1H3/b11-10+/t13-,14+/m0/s1. InChi Key: VDRZDTXJMRRVMF-NXFSIWHZSA-N.