Progesterone-d9

Progesterone-d9 is intended for use as an internal standard for the quantification of progesterone (Cay-15876) by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Delta4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.Formal Name: pregn-4-ene-3,20-dione-2,2,4,6,6,17,21,21,21-d9. CAS Number: 15775-74-3. Synonyms: Cyclogest-d9. Molecular Formula: C21H21D9O2. Formula Weight: 323.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: 1 mg/ml, Ethanol: 1 mg/ml, Methanol: 1 mg/ml. SMILES: C[C@@]12[C@](CC[C@]2([2H])C(C([2H])([2H])[2H])=O)([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC1)=O. InChi Code: InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1/i1D3,4D2,8D2,12D,17D. InChi Key: RJKFOVLPORLFTN-PQIPVKAESA-N.