Prednicarbate

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone (Cay-20866). It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema.Formal Name: (11beta)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione. CAS Number: 73771-04-7. Synonyms: Prednisolone 17-(ethyl carbonate) 21-propionate, S 77-0777. Molecular Formula: C27H36O8. Formula Weight: 488.6. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Slightly Soluble, Ethanol: Slightly Soluble, Methanol: Slightly Soluble. SMILES: [H][C@]12[C@@]([C@@](CC[C@]3(OC(OCC)=O)C(COC(CC)=O)=O)([H])[C@]3(C)C[C@@H]2O)([H])CCC4=CC(C=C[C@@]41C)=O. InChi Code: InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1. InChi Key: FNPXMHRZILFCKX-KAJVQRHHSA-N.