PAMAM Dendrimer G4.0 Amine (water solution)

PAMAM Dendrimer G4.0 Amine (water solution)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39074-500 500 mg -

6 - 10 business days*

243.00€
Cay39074-1 1 g -

6 - 10 business days*

463.00€
 
PAMAM dendrimer G4.0 amine (PAMAM G4.0) is a polyamidoamine (PAMAM) dendrimer with amine termini... more
Product information "PAMAM Dendrimer G4.0 Amine (water solution)"
PAMAM dendrimer G4.0 amine (PAMAM G4.0) is a polyamidoamine (PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vivo. It is approximately 45 Å in diameter and has 64 surface groups. It inhibits fibril formation by alpha-synuclein in a cell-free assay when used at concentrations of 1 and 2 µM. PAMAM G4.0 is active against E. coli (IC50 = 3.8 µg/ml) and toxic to zebrafish embryos, inducing mortality at 120 hours post-fertilization when used at concentrations ranging from 0.5 to 20 µM. PAMAM G4.0 (100 and 300 mg/kg) in complex with the topoisomerase I inhibitor camptothecin (Cay-11694) increases the oral bioavailability of camptothecin in mice without inducing gastrointestinal toxicity. PEG-modified PAMAM G4.0 in complex with folic acid (Cay-20515), 5-fluorouracil (5-FU, Cay-14416), and the imaging agent technetium-99m (PEG-PAMAM G4-FA-5FU-99mTc) localizes to the tumor, as well as the liver and spleen, in a 4T1 murine mammary tumor model.CAS Number: 163442-67-9. Synonyms: PAMAM G4.0, Polyamidoamine Dendrimer G4.0. Molecular Formula: [NH2(CH2)2NH2]:(G=4),dendri PAMAM(NH2)64. Formula Weight: 14214.2. Formulation: (Request formulation change), A solution in water. Solubility: Water: Soluble.
Keywords: PAMAM G4.0, Polyamidoamine Dendrimer G4.0
Supplier: Cayman Chemical
Supplier-Nr: 39074

Properties

Application: Amine-terminated PAMAM dendrimer, in vivo drug delivery
MW: 14214.2 D
Formula: [NH2(CH2)2NH2]:(G=4),dendri PAMAM(NH2)6...
Format: Solution

Database Information

CAS : 163442-67-9| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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