PAMAM Dendrimer G2.0 Amidoethanol (water solution)

PAMAM Dendrimer G2.0 Amidoethanol (water solution)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39111-500 500 mg -

6 - 10 business days*

122.00€
Cay39111-1 1 g -

6 - 10 business days*

231.00€
 
PAMAM dendrimer G2.0 amidoethanol (PAMAM G2.0 amidoethanol) is a polyamidoamine (PAMAM) dendrimer... more
Product information "PAMAM Dendrimer G2.0 Amidoethanol (water solution)"
PAMAM dendrimer G2.0 amidoethanol (PAMAM G2.0 amidoethanol) is a polyamidoamine (PAMAM) dendrimer with hydroxyl termini that has been used as a drug delivery system in vitro. It is approximately 29.4 Å in diameter in water and has 16 surface groups. PAMAM G2.0 amidoethanol is an antagonist of the pore-forming channel binary anthrax toxin protective antigen 63 (PA63) in lipid bilayers (IC50 = 142 nM). It inhibits the proliferation of MCF-7 and MDA-MB-231 breast cancer cells when used at a concentration of 100 µM. PAMAM G2.0 amidoethanol enhances the water solubility of the antibiotic erythromycin (Cay-16486) and increases the antifungal activity of clotrimazole (Cay-15278) against Candida. Fragmentation of PAMAM G2.0 amidoethanol with hydrogen peroxide produces a fluorescent unsaturated hydroxylamine, which selectively detects hypochlorite over several other reactive oxygen species (ROS) and has been used to detect intracellular hypochlorite levels in RAW 246.7 macrophages.Synonyms: PAMAM G2.0 Amidoethanol, Polyamidoamine Dendrimer G2.0 Amidoethanol. Molecular Formula: [NH2(CH2)2NH2]:(G=2),dendri PAMAM(NHCH2CH2OH)16. Formula Weight: 3271.9. Formulation: (Request formulation change), A solution in water. Solubility: Water: soluble.
Keywords: PAMAM G2.0 Amidoethanol, Polyamidoamine Dendrimer G2.0 Amidoethanol
Supplier: Cayman Chemical
Supplier-Nr: 39111

Properties

Application: Hydroxyl-terminated PAMAM dendrimer
MW: 3271.9 D
Formula: [NH2(CH2)2NH2]:(G=2),dendri PAMAM(NHCH2CH2OH)16
Format: Solution

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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