PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay39104-500 500 mg -

6 - 10 business days*

103.00€
Cay39104-1 1 g -

6 - 10 business days*

196.00€
 
PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with... more
Product information "PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)"
PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. It is approximately 27.9 Å in diameter in water and has 8 surface groups. Conjugates of PAMAM G0.5 with the active fragment of the DNA cross-linking agent oxaliplatin (Cay-13106) are cytotoxic to A2780 ovarian, MCF-7 breast, and Caco-2 colon cancer cells and BJ fibroblasts (IC50s = 0.03, 1.6, 0.18, and 3 µM, respectively).Formal Name: 11,14-bis[3-[[2-[bis(2-carboxyethyl)amino]ethyl]amino]-3-oxopropyl]-4,21-bis(2-carboxyethyl)-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanedioic acid, octasodium salt. CAS Number: 339334-01-9. Synonyms: PAMAM G0.5 Carboxylate, Polyamidoamine Dendrimer G0.5 Carboxylate. Molecular Formula: C46H72N10O20 . 8Na. Formula Weight: 1269.1. Formulation: (Request formulation change), A solution in water. Solubility: Water: Soluble. SMILES: O=C(NCCN(CCC([O-])=O)CCC([O-])=O)CCN(CCC(NCCN(CCC([O-])=O)CCC([O-])=O)=O)CCN(CCC(NCCN(CCC([O-])=O)CCC([O-])=O)=O)CCC(NCCN(CCC([O-])=O)CCC([O-])=O)=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C46H80N10O20.8Na/c57-35(47-13-29-51(21-5-39(61)62)22-6-40(63)64)1-17-55(18-2-36(58)48-14-30-52(23-7-41(65)66)24-8-42(67)68)33-34-56(19-3-37(59)49-15-31-53(25-9-43(69)70)26-10-44(71)72)20-4-38(60)50-16-32-54(27-11-45(73)74)28-12-46(75)76,,,,,,,,/h1-34H2,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,71,72)(H,73,74)(H,75,76),,,,,,,,/q,8*+1/p-8. InChi Key: HLBBXYHSZWSLRS-UHFFFAOYSA-F.
Keywords: Polyamidoamine Dendrimer G0.5 Carboxylate, PAMAM G0.5 Carboxylate, 11,14-bis[3-[[2-[bis(2-carboxyethyl)amino]ethyl]amino]-3-oxopropyl]-4,21-bis(2-carboxyethyl)-8,17-dioxo-4,7,11,14,18,21-hexaazatetracosanedioic acid, octasodium salt
Supplier: Cayman Chemical
Supplier-Nr: 39104

Properties

Application: Carboxylate-terminated PAMAM dendrimer
MW: 1269.1 D
Formula: C46H72N10O20 . 8Na
Format: Solution

Database Information

CAS : 339334-01-9| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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