Palmityl Trifluoromethyl Ketone

PTK is an analog of palmitic acid in which the COOH group is replaced by trifluoromethyl ketone. In P388D1 cells, PTK inhibits iPLA2 activity with an IC50 value of 3.8 µM. A related compound, ATK is a less potent inhibitor of iPLA2 with an IC50 value of 15 µM. PTK also inhibits the activity of cPLA2 with an IC50 value almost identical to that of ATK.Formal Name: 1,1,1-trifluoro-2-heptadecanone. CAS Number: 141022-99-3. Synonyms: Pentadeca Trifluoromethyl Ketone, PTK. Molecular Formula: C17H31F3O. Formula Weight: 308.4. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: basic PBS: freely soluble, DMF: >50 mg/ml, DMSO: >30 mg/ml, Ethanol: >50 mg/ml, PBS pH 7.2: <50 µg/ml (from ATK). SMILES: CCCCCCCCCCCCCCCC(=O)C(F)(F)F. InChi Code: InChI=1S/C17H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(21)17(18,19)20/h2-15H2,1H3. InChi Key: MAHYXYTYTLCTQD-UHFFFAOYSA-N.